Manufacturing and Supplying the Products Used in Aquatic Animal Medicine
IAAAM Archive
Dr. Donald F. Amend, Director of Research
Tavoek Laboratories, Inc., Redmond, WA

Abstract

A discussion of the development of equipment, drugs, chemicals, and materials used to treat, nourish, handle, and contain aquatic animals.

Notes

Tavolek fish health products have world-wide scope. Production is done by Pitman-Moore labs.

Aquaculture - better techniques are needed in fish culture, disease control, genetics and nutrition.

New Product Requirements

Vaccines - have been developed for Vibrio and Enteric red mouth.

Antifungals, growth promotants, antibiotics, anesthetics, tranquillizers, endocrines, diagnostics, disinfectants and parasiticides are needed.

New delivery techniques - vaccination methods such as direct immersion and the shower method are being studied.

Procedures used to bring a new fish vaccine to market:

  • Ascertain current status of problem

    • mortality, morbidity, incidence.

    • disease control possible?

    • drug resistance exists?

  • Disease situation

    • refractory to treatment

    • organisms are drug resistant

    • problem in delivery of treatment

    • not treatable

  • A working strain is cultured, then treated (for example by attenuation).

  • It is tested parenterally and orally and various topical methods such as immersion, shower-spray and hyperosmotic treatment are used.

  • Vaccinated fish are challenged to see whether or not they are protected.

  • An outline of the production of a successful bacterin is sent to the USDA for approval.

  • The vaccine is field tested.

  • Further development - shelf life, use with other species, onset and duration data, cross-protection studies are considered.

The FDA has to grant a license before the vaccine can be marketed.

Speaker Information
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Donald F. Amend
Tavolek Laboratories


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