Administration of intravenous fluids is one of the most frequent therapeutic options in critical care. However, it is about time that fluids should be treated as drugs. A conceptual framework of the 7 Ds is presented with a focus on definitions (fluid status, preload, fluid responsiveness), diagnosis (hypo-, eu-, and hypervolemia, organ and tissue perfusion), drug (type of fluids, indications, contraindications, adverse effects, rate, objectives and limits), dose, duration, de-escalation, and discharge. The four indications for fluid administration will be discussed: resuscitation, maintenance, replacement and nutrition. The four questions: when to start IV fluids, when to stop them, when to start fluid evacuation and when to stop fluid removal. The four phases and the ROSE concept: resuscitation, optimization, stabilization and evacuation. The four hits, the four compartments and much more. It is time for fluid stewardship, defined as a series of coordinated interventions, introduced to select the optimal fluid, dose and duration of therapy that results in the best clinical outcome, prevention of adverse events and cost reduction…