A male, adult tiger (Panthera tigris) was anesthetized for the routine exam to accomplishment medicine practice in October 2005, during which we can evidence presence of periodontal disease. However, the accomplishment of the dental treatment was not possible in the moment, because there were not the necessary equipments. After 30 months, a new chemical contention for general evaluation was necessary, because the animal presented anorexia, polydipsia and progressive weight loss. At this time, we were observed the presence of tumor measuring approximately 2cm of diameter, smooth surface, regular and color pink in upper left canine tooth. Complete periodontal treatment was accomplished and the tumor was surgically removed, with aid of electric scalpel and directed for histopathological evaluation. Histological sections of oral mucosa showing: ulcerative lesion partially covered by pavement stratified epithelium; presence of ulcerated areas of mixed inflammatory infiltrate; acanthotic oral epithelium with preservation of cellular differentiation of keratinocytes; stromal increase, particularly in submucosa, with high density, fibroblast cells identifying himself with loose chromatin and evident nucleoli, indicating intense metabolic activity; important component collagen, with outbreaks of deposition of hyaline matrix acidophilic and frequent mineralization; absent of odontogenic epithelium and malignancy. Evidencing a fibromatous epulis. Epulis is a nonspecific, clinical descriptive term referring to a benign local exophytic growth of the oral mucosa. Epulides are microscopically characterized by a dense, well vascularized stroma, populated by cells with abundant collagen fibrils resembling the periodontal ligament. Feline (domestic) epulides are infrequently, representing up to 7.8% he is fibromatous type and up to 0.5% for the giant cell epulis of all feline oral neoplasms. Most domestic feline epulides are single, but multiple occurrences are reported in the fibromatous type and tend to have a higher rate recurrence after surgery. There are three histologic types of epulides: fibromatous epulis, ossifying epulis and acanthomatous epulis. This classification was based on their clinical appearance and behavior. There are no reports of fibromatous epulis in zoo and wild tigers. Unhappily this tiger died after three months as a consequence of serious renal disease.