Keynote Message

"Triaditis" is the term used to describe concurrent inflammation of the pancreas, liver, and small intestines. Triaditis has been reported in 50–56% of cats diagnosed with pancreatitis and 32–50% of those with cholangitis/inflammatory liver disease. A definitive diagnosis of triaditis is based on the histopathological evaluation of each organ. However, the specific conditions of each organ that constitute a diagnosis triaditis remains to be defined. While the etiopathogenesis of pancreatitis and its relationship to inflammation in other organ systems is unclear, preliminary studies point to a heterogeneous group of conditions with differential involvement of host inflammatory and immune responses and enteric bacteria. Comprehensive, prospective studies that simultaneously evaluate the presence of pre-defined clinical, clinicopathological, and histopathological abnormalities, coupled with high-resolution evaluation of pancreaticobiliary morphology, immunological profiling, and screening for bacterial colonization are required to advance diagnosis and therapy.

Key References

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