S. Frasca Jr.1, VMD; J. L. Dunn1, VMD; John C. Cooke2, PhD; John D. Buck1,2, PhD
Fusarium species are ubiquitous soil saprophytes and plant
pathogens. In human patients, Fusarium species are known to infect the cornea, nails, and
bum eschars of healthy individuals and disseminated infections are reported in immunosuppressed
individuals (Hiemenz, et al. 1990). Superficial and deep Fusarium infections are
similarly chronicled in a myriad of animals, such as sharks, sea turtles, fish, pinnipeds (e. g.
California sea lions and grey seals), horses, cattle, and an alligator (Smith, et al.
1989). A number of Fusarium species are recognized as etiologic agents of
disease.
The occurrence of Fusarium associated dermatitides involving an
Atlantic white-sided dolphin, a pygmy sperm whale, and a harbor seal at Mystic Marin life
Aquarium is reported. In each case, the infected animal had incurred some major, recent stressor
(i.e. stranding, long distance transport, relocation). The lesions appeared as raised, firm
nodules with erythematous, ulcerated, and sometimes friable surfaces. The nodules extended over
the heads, trunks, and posterior portions of the animals. Microbial cultures revealed fungal
elements in addition to various bacterial agents, such as Staphylococcus and
Enterobacter. Culturing of the fungal isolates on multiple media demonstrated the
characteristic reproductive structures associated with Fusarium species. Concomitant
histopathologic examination of biopsy specimens from each individual confirmed the presence of
fungal elements consistent with those of a zygomycete within epidermal tissues. Ketaconazole was
administered per os in conjunction with antibacterial therapy, and the representative dermatitis
of each individual resolved.
Dermatitis associated with Fusariunt species infection was identified
and treated in two species of cetacean and one species of pinniped. Fusarium species may
be opportunistic invaders in cases involving immunosuppression and/or integumentary
compromise.