Bladder augmentation or Ileocystoplasty is addition of a bowel segment to the bladder in situ to increase capacity, improve compliance, and/or abate on controllable detrusor. This study was conducted to evaluate hematological and biochemical changes following Ileocystoplasty in dogs.

Twelve Persian mixed breed female dogs between 1-2 year-old and 15-24 kg body-weight were divided into control and experiment groups. Routine Ileocystoplasty was performed on experimental dogs. Blood samples were drawn for hematological and biochemical evaluations on days 0, 14 and 35 from all animals.

A mixed-model (repeated-measure) analysis of variance was used to compare the means of quantitative variables at different times. No significant changes were found in hematologic parameters (WBC, RBC, neutrophil, lymphocyte, monocyte, eosinophil, basophil, hematocrit, and platelets), glucose, cholesterol, triglyceride, creatinine, total protein, albumine, glutamine, serum electrolytes (calcium, potassium, phosphorus, sodium, chloride and bicarbonate), albumin, PH, blood gases (PO₂ and PCO₂) and anion gap. BUN was found significantly higher in experiment group in comparison to control group.

Routine ileocystoplasty found to have minimal effect on hematological and biochemical parameters and is recommended in reconstruction of diseased bladder.