Successful microscope evaluation of a specimen depends on the quality of the sample. This seminar will focus on how to collect and process a sample such that a good quality slide and/or fluid sample amenable to cytologic evaluation and fluid analysis is prepared. A systematic approach to the evaluation of a cytologic specimen will be introduced. By the end of this seminar, you will walk away with practical tips to avoid non-diagnostic results, an approach to diagnosing disease from fine needle cell aspirates of lumps and bumps and harvesting cells present in body fluids and washes.