Intrathecal mepivacaine after general anesthesia is an effective method of equine euthanasia when compared to intravenous pentobarbital.

Am J Vet Res. May 2023;84(5):.

Kate Alexander, Embry Simon, Khursheed Mama, Sangeeta Rao, Luke Bass

Abstract

OBJECTIVES:This study aims to assess intrathecal mepivacaine for euthanasia in anesthetized horses and compare it to a traditional euthanasia method using a single intravenous injection of pentobarbital in sedated horses.

ANIMALS:Client-owned horses and horses requiring euthanasia due to involvement in concurrent research projects were used. Horses were randomly assigned to 1 of 2 groups: intrathecal mepivacaine after anesthesia or intravenous pentobarbital after sedation. All horses had normal vital parameters and no signs of infectious disease at the time of euthanasia.

PROCEDURES:The intrathecal mepivacaine group was anesthetized before the intrathecal injection of mepivacaine. The pentobarbital group was sedated, concurrently anesthetized and euthanized using intravenous pentobarbital, then received an intrathecal saline (0.9% NaCl) solution injection to a blind observer. Both groups were sedated with detomidine and the time from sedation to the cessation of vital parameters (respirations, pulse, corneal reflex, and ECG) was recorded. Euthanasias were recorded for review by a blinded anesthesiologist, using an independent scale to assess the quality of sedation, anesthesia induction, and lateral recumbency.

RESULTS:Time from detomidine administration to cessation of each vital parameter was significantly longer in the intrathecal mepivacaine group. There was no statistically significant difference in qualitative scores between groups for sedation or induction, but lateral recumbency was subjectively superior in the anesthetized intrathecal mepivacaine group.

CLINICAL RELEVANCE:Intrathecal mepivacaine provided a safe, effective, alternative method of euthanasia to intravenous pentobarbital and addresses concerns about barbiturate availability. This study also informs practitioners of what to expect (ie, longer cessation of vital parameters) when using the intrathecal mepivacaine method.

Article Tools:

Medline

Email to me

Archives Highlights:

The relationship between radiographic disc calcification score and FGF4L2 genotype in dachshunds.
Most dachshunds with 1 FGF4L2 copy have radiographic disc calcification scores that are associated with substantially lower risk of symptomatic disc disease. Radiographic disc calcification scores are similar in dachshunds with 0 and 1 FGF4L2 copies. Given the high allele frequency of FGF4L2, breeding to produce progeny with 1 FGF4L2 copy is expected to be a more achievable short-term goal for dachshund spinal health breeding programs than breeding for 0 copies. It is recommended that both K-n and FGF4L2 genotype status be considered when choosing dachshund breeding stock.

"My Bitch Is Empty!" An Overview of the Reasons for Pregnancy Loss in Dogs.
If embryonic death occurs before day 35 of gestation, the embryo is absorbed. Fetal death in the second half of gestation leads to abortion or fetal emphysema, maceration, or mummification.

Canine distemper outbreak and laryngeal paralysis in captive tigers (Panthera tigris).
All suspected and confirmed cases of CDV infections were significantly associated with laryngeal inflammation, which developed into paralysis in almost 50% of cases. Altogether, 50% of all tiger cases with chronic infection developed stridor at 314 days after virus infection. Therefore, laryngeal paralysis may result from CDV infection and degeneration, potentially affecting the peripheral and central nervous systems. This condition could pose a life-threatening risk to tigers.

National survey reveals elastic price sensitivity for select equine veterinary services.
Willingness-to-pay questions were presented with a payment card approach and addressed 3 common services: annual spring vaccinations, lameness examinations, and emergency colic surgeries. In a payment card approach, respondents choose from among preselected values. Respondents were asked to choose the maximum amount they would be willing to pay for each service.

A public health campaign to increase awareness of the risk of dog bites in South Australia.
Over one third (36-37%) of dog owners and 25-29% of non-dog owners had been previously bitten by a dog, although most did not require medical attention. Approximately 70% of dog owners believed it was safe for strangers to approach their dog, 34-37% allowed children or other people to pat their dog without permission, and less than half separated their dog from visitors or delivery people. In contrast, few of the non-dog owners allowed their children to pat a dog without the owner's permission and only 2% allowed them to play with dogs without supervision.